Multimorbidity patterns in people with Alzheimer’s disease
نویسندگان
چکیده
Background Multimorbidity is highly impactful for older adults, especially when it co-occurs with Alzheimer’s disease (AD). However, scarce evidence available about comorbid conditions co-occurring AD. We aimed to identify the most prevalent and examine common multimorbidity patterns in patients Method Using electronic health records of a university hospital, we extracted data from 2,646 adults AD (ICD-10) using Calderón-Larrañaga’s inventory chronic conditions. Leverage correlation was performed detect patterns. Result had on average 13 50% them at least 10 Hypertension (51.7%), lipoprotein metabolism disorders other lipidemia (35%), depression (33.9%), general mental (31.96%), sleep (26%), urinary (25.3%), anemia (24.6%), joint (23.19%), kidney (21.25%), functional intestinal (20.66%) were top The “disorders lipidemia” “hypertension” (frequency [n = 747, 30%]; leverage:0.09), followed by “hypertensive disease” 189, 8%]; leverage:0.06), “presence cardiac vascular implants grafts” lipidemias” 181,7%; leverage:0.05), “Type 2 diabetes” “hypertension leverage:0.05).” Conclusion Our results align prior studies that cardiovascular disease, diabetes, osteoarthritis, are people These findings might support future investigating mechanisms linking AD, which ultimately can guide preventive actions comprehensive approaches managing these
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ژورنال
عنوان ژورنال: Alzheimers & Dementia
سال: 2023
ISSN: ['1552-5260', '1552-5279']
DOI: https://doi.org/10.1002/alz.064414